A newly discovered chemical pathway that helps protect heart tissue can be stimulated by two of 20 common beta-blockers, drugs that are prescribed to millions of patients who have experienced heart failure.
Researchers from Duke University Medical Center tested 20 beta blockers and found that two of them -- alprenolol and carvedilol -- could stimulate a pathway recently found to protect heart tissue.
This finding could guide future drug development and in particular help heart failure patients, says Howard Rockman, MD, senior author of the study and chief of the Duke Cardiology Division.
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